Journal: The journal of trauma and acute care surgery

Article Title: Effects of platelet-sparing leukocyte reduction and agitation methods on in vitro measures of hemostatic function in cold-stored whole blood

doi: 10.1097/TA.0000000000001870

Figure Lengend Snippet: Viscoelastic measures in nonleukoreduced and leukoreduced WB units over time. This figure shows viscoelastic measures of non-LR (blue bars) and LR (green bars) whole blood units over 15 days. These include the MCF measured by ROTEM (A), MA measured by TEG (B), TEG MA-ADP (C), and TEG MA-AA (D). Median measurements of MCF, TEG MA, TEG MA-ADP, and TEG MA-AA were compared at each time point between LR and non-LR groups, and absolute median measurements were compared from Day 0 to Day 15 within LR or non-LR groups. Differences are indicated by *p < 0.05, **p < 0.01, ***p < 0.001.

Article Snippet: Hemostatic parameters were measured using viscoelastic assays (rotational thromboelastometry-Extrinsic Screening Test (ROTEM-EXTEM) and thromboelastography (TEG) platelet mapping), impedance aggregometry (agonists—adenosine phosphate, arachidonic acid, thrombin receptor activating peptide, and collagen), and a thrombin generation assay from these whole blood units before and after filtration and on 0, 5, 10, and 15 days of storage at 4°C.

Techniques:

Journal: The journal of trauma and acute care surgery

Article Title: Effects of platelet-sparing leukocyte reduction and agitation methods on in vitro measures of hemostatic function in cold-stored whole blood

doi: 10.1097/TA.0000000000001870

Figure Lengend Snippet: Viscoelastic measures in leukoreduced WB units by agitation method over time. This figure shows viscoelastic measures of LR WB units by differing agitation method over 15 days. Agitation methods included un-rocked (blue bar; none), up and down shake (green bar), continuous mechanical horizontal agitation via flat rocker (yellow bar), or continuous end-over-end rocking via a 360° rotator (red). The viscoelastic parameters measured include the MCF measured by ROTEM (A), MA measured by TEG, (B), TEG MA-ADP (C), and TEG MA-AA (D). Median measurements of MCF, TEG-MA, TEG MA-ADP, and TEG MA-AA were compared at each time point. No differences were noted. Median measurements of MCF, TEG-MA, TEG MA-ADP, and TEG MA-AA were compared within each agitation group from Day 0 to Day 15. Differences are indicated by *p < 0.05, **p < 0.01, ***p < 0.001.

Article Snippet: Hemostatic parameters were measured using viscoelastic assays (rotational thromboelastometry-Extrinsic Screening Test (ROTEM-EXTEM) and thromboelastography (TEG) platelet mapping), impedance aggregometry (agonists—adenosine phosphate, arachidonic acid, thrombin receptor activating peptide, and collagen), and a thrombin generation assay from these whole blood units before and after filtration and on 0, 5, 10, and 15 days of storage at 4°C.

Techniques:

Journal: The journal of trauma and acute care surgery

Article Title: Effects of platelet-sparing leukocyte reduction and agitation methods on in vitro measures of hemostatic function in cold-stored whole blood

doi: 10.1097/TA.0000000000001870

Figure Lengend Snippet: Viscoelastic measures in nonleukoreduced WB units by agitation method over time. This figure shows viscoelastic measures of non-LR WB units by differing agitation method over 15 days. Agitation methods included un-rocked (blue bar; none), up and down shake (green bar), continuous mechanical horizontal agitation via flat rocker (yellow bar), or continuous end-over-end rocking via a 360° rotator (red). Viscoelastic parameters measured include MCF measured by ROTEM (A), MA measured by TEG (B), TEG MA-ADP (C), and TEG MA-AA (D). Median measurements of MCF, TEG-MA, TEG MA-ADP, and TEG MA-AA were compared at each time point, and absolute median measurements were compared within each agitation method form Day 0 to Day 15.Differences are indicated by *p < 0.05, **p < 0.01, ***p < 0.001.

Article Snippet: Hemostatic parameters were measured using viscoelastic assays (rotational thromboelastometry-Extrinsic Screening Test (ROTEM-EXTEM) and thromboelastography (TEG) platelet mapping), impedance aggregometry (agonists—adenosine phosphate, arachidonic acid, thrombin receptor activating peptide, and collagen), and a thrombin generation assay from these whole blood units before and after filtration and on 0, 5, 10, and 15 days of storage at 4°C.

Techniques:

Journal: Wellcome Open Research

Article Title: Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial

doi: 10.12688/wellcomeopenres.14722.1

Figure Lengend Snippet: Baseline characteristics by treatment group (N=167).

Article Snippet: Thromboelastometry (ROTEM® EXTEM) , , , , , , , , .

Techniques: Cell Counting, Coagulation

Journal: Wellcome Open Research

Article Title: Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial

doi: 10.12688/wellcomeopenres.14722.1

Figure Lengend Snippet: Effect of tranexamic acid (TXA) on coagulation and fibrinolysis in women with postpartum haemorrhage.

Article Snippet: Thromboelastometry (ROTEM® EXTEM) , , , , , , , , .

Techniques: Coagulation